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Welcome back to SERious Epidemiology! This is the first official episode of the fifth season of SERious Epidemiology. This season we’ll be discussing the textbook Causal Inference: What If. Chapter 1 discusses foundational concepts of causal inference, including identifiability assumptions, counterfactuals, individual vs. population-level causal effects, and null effects. We talk about the example of Greek gods and goddesses and the notation (e.g., Y for the outcome) used throughout the textbook. In this episode, we hope to highlight the concept that causal effects involve a comparison. Matt also offers a hot take comparing the identifiability assumptions to the Marvel cinematic universe: exchangeability is Captain America, consistency is the Hulk, positivity Ironman, the no interference assumption is Groot. Do you agree?