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In this episode of Season 2 of SERious Epidemiology, Hailey and Matt connect with Dr. Jon Huang for a discussion on precision and study size. We wade into whether or not we should use p-values. We discuss whether the debates on p-values are real or just on Twitter and whether they should be used in observational epi or just in trials. We ask whether p-values do more harm than good in observational studies or whether the harm is really around null hypothesis significance testing. We talk about misconceptions about p-values. And Jon tells us how he’s going to win a gold medal in the Winter Olympics, despite living in a tropical climate.